Dizeres Legais - Willentine

Registro MS: 1.5832.0002

Farmacêutico Responsável:
Luciane Mazzai Maguiroski
CRF-SC N.º 3793

Registrado por:
Mawdsleys Pharmaceuticals do Brasil Ltda.
Rua Alameda Joaquim Eugênio de Lima, 680 Conj 34
CEP 01403-000 - Jardim Paulista – São Paulo, São Paulo
CNPJ: 19.501.429/0001-90

Faricado por:
Apothecon Pharmaceuticals Pvt. Limited.
Padra-Jambusar Highway
Tal-Padra, Village-:Dabhasa - 391 440
Vadodara, Gujarat, India

Importado e distribuído por:
Mawdsleys Pharmaceuticals do Brasil Ltda.

SAC
0800 591 2745

Venda sob prescrição médica.

Referências
1. Syprine product information (MSD—US), Rev 3/89, Rec 11/89.
2. Harada M, Miyagawa K, Honma Y, et al. Excess copper chelating therapy for Wilson disease induces anemia and liver dysfunction. Intern Med. 2011;50(14):1461-1464. doi:10.2169/internalmedicine.50.5209.
3. Brewer GJ, Askari F, Lorincz MT, et al. Treatment of Wilson Disease with ammonium tetrathiomolybdate: IV. Comparison of tetrathiomolybdate and trientine in a double-blind study of treatment of the neurologic presentation of Wilson disease. Arch Neurol. 2006;63(4):521-527. doi:10.1001/archneur.63.4.521.
4. Perry AR, Pagliuca A, Fitzsimons EJ, Mufti GJ, Williams R. Acquired sideroblastic anaemia induced by a copperchelating agent. Int J Hematol. 1996;64(1):69-72. doi:10.1016/0925-5710(96)00457-4.
5. Dahlman T, Hartvig P, Löfholm M, Nordlinder H, Lööf L, Westermark K.
6. Long-term treatment of Wilson’s disease with triethylene tetramine dihydrochloride (trientine). Q J Med. 1995;88:609–16.
7. Jang HJ, Jang JY, Kim KM. Appendiceal Orifice Inflammation in an 8-Year-Old Girl with Ulcerative Colitis Complicating Wilson's Disease. Gut Liver. 2010 Mar;4(1):126-8. doi: 10.5009/gnl.2010.4.1.126. Epub 2010 Mar 30. PMID: 20479926; PMCID: PMC2871613.
8. Boga S, Jain D, Schilsky ML. Trientine induced colitis during therapy for Wilson Disease: a case report and review of the literature. BMC Pharmacol Toxicol. 2015 Nov 20;16:30. doi: 10.1186/s40360-015-0031-z. PMID: 26589720; PMCID: PMC4654910.
9. Zimbrean PC, et al. The spectrum of psychiatric symptoms in Wilson&apos´s Disease: Treatment and prognostic considerations. American Journal of Psychiatry 172: 1068-1072, No. 11, Nov 2015 – USA.
10. Kim B, Chung SJ, Shin HW. Trientine-induced neurological deterioration in a patient with Wilson's Disease. J Clin Neurosci. 2013;20(4):606-608. doi:10.1016/j.jocn.2012.02.041.
11. Roberts EA, Schilsky ML; American Association for Study of Liver Diseases (AASLD). Diagnosis and treatment of Wilson disease: an update. Hepatology. 2008;47(6):2089-2111. doi:10.1002/hep.22261.
12. Weiss KH, Thurik F, Gotthardt DN, et al. Efficacy and safety of oral chelators in treatment of patients with Wilson Disease. Clin Gastroenterol Hepatol. 2013;11(8):1028-35.e352. doi:10.1016/j.cgh.2013.03.012.
13. Weiss KH, Gotthardt DN, Klemm D, et al. Zinc monotherapy is not as effective as chelating agents in treatment of Wilson Disease. Gastroenterology. 2011;140(4):1189-1198.e1. doi:10.1053/j.gastro.2010.12.034.
14. Roberts EA, Schilsky ML; American Association for Study of Liver Diseases (AASLD). Diagnosis and treatment of Wilson Disease: an update. Hepatology. 2008;47(6):2089-2111. doi:10.1002/hep.22261.
15. Epstein O, Sherlock S. Triethylene tetramine dihydrochloride toxicity in primary biliary cirrhosis. Gastroenterology. 1980;78(6):1442-1445.